Supplement Collections and Wellness Guides

OmneDiem offers an array of digestive enzymes, cognitive support supplements, and cutting-edge, high-quality, pure formulations in Creatine and beyond. In addition, OmneDiem specializes in enzyme-based supplements for people managing dietary histamine and everyday digestive comfort — including Histamine Digest®, a diamine oxidase (DAO) enzyme supplement that helps break down histamine from food and drink. Use this guide to find the right collection, or start with our educational articles if you're new to DAO and histamine.

Not sure where to start? Browse our most popular supplements, or learn the science first:

Shop by Collection

  • OmneDiem DAO enzyme supplements for dietary histamine support

    DAO Enzyme Supplements

    Diamine oxidase (DAO) enzyme formulas — including Histamine Digest® "The Original," PureMAX 40,000 HDU, and Histamine Digest 360 with vitamin B6 — that help break down dietary histamine before it's absorbed.

    Shop DAO Supplements →
  • OmneDiem Superzymes digestive enzyme supplement bottle

    Digestive Enzyme Supplements

    Broad-spectrum enzyme blends like Superzymes and Ultra Proteo-Zimes™ that support nutrient breakdown, gut function, and daily digestive comfort.

    Explore Digestive Enzymes →
  • OmneDiem Max Absorb micronized creatine with Creavitalis, unflavored powder

    Micronized Creatine — Max Absorb

    Unflavored creatine monohydrate powder made with single-sourced German Creavitalis®, micronized for easy mixing and absorption. 5 g per serving to support strength, recovery, and cognitive performance.

    Shop Max Absorb Creatine →
  • Guide to symptoms of histamine intolerance from OmneDiem's education hub

    Learn: Enzyme & Histamine Education

    Evidence-informed articles on DAO enzymes, histamine in foods and drinks, low-histamine eating, and gut health — written to help you shop with confidence.

    Visit the Education Hub →
  • Histamine Digest The Original 30,000 HDU DAO enzyme supplement, an OmneDiem best seller

    Best Sellers

    Our most popular formulas — Histamine Digest®, PureMAX, Histamine Digest 360, and Drink HD — trusted by customers for daily digestive and dietary histamine support.

    Shop Best Sellers →
  • OmneDiem Drink HD DAO enzyme supplement available on subscription

    Subscribe & Save 10%

    Get your supplements delivered automatically and save 10% on every order. Pause, skip, or expedite shipments anytime — you stay in control.

    Start a Subscription →

Which Collection Is Right for You?

If you… Start here
React to histamine-rich foods or drinks (aged cheese, wine, fermented foods) DAO Enzyme Supplements
Want everyday digestion and nutrient-absorption support Digestive Enzyme Supplements
Are focused on strength, recovery, and performance Max Absorb Creatine
Are new to DAO and want to understand the science first Education Hub · DAO FAQ
Already know what works and want it on autopilot Subscribe & Save

Frequently Asked Questions

What is a DAO enzyme supplement?

Diamine oxidase (DAO) is the enzyme your body uses to break down histamine from food and drink. A DAO enzyme supplement, taken shortly before meals, provides extra DAO in the digestive tract to help break down dietary histamine before it's absorbed. Learn more in What Is Diamine Oxidase?

Which OmneDiem supplement should I start with?

Most customers managing dietary histamine start with Histamine Digest®, our original DAO enzyme formula. For higher-potency support, see PureMAX (40,000 HDUs); for general digestion, start with our digestive enzyme blends.

Which foods are high in histamine?

Aged cheeses, cured meats, fermented foods, vinegar, alcohol (especially red wine), and leftovers tend to be high in histamine. See our guides to foods high in histamine and the low-histamine shopping list.

Does OmneDiem offer subscriptions?

Yes — subscribe to any eligible product for automatic delivery and save 10% on every order, with free shipping and the flexibility to pause, skip, or expedite shipments anytime. Details on our subscription page.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.