What does DAO (diamine oxidase) do?

DAO is the primary enzyme that breaks down histamine in your digestive tract. When DAO activity is low, dietary histamine can accumulate and trigger sensitivity reactions.

What is DAO deficiency?

DAO deficiency means your body produces too little diamine oxidase to keep up with the histamine in your diet. It is a leading cause of histamine intolerance and can be supported by supplementing DAO before meals.

When should I take Histamine Digest?

Take Histamine Digest shortly before consuming high-histamine foods and beverages, so the DAO enzyme is present in your digestive tract as you eat.

Is Histamine Digest a medication or an antihistamine?

No. Histamine Digest is a dietary supplement that supplies the DAO enzyme to support histamine breakdown in digestion. It is not a drug and does not block histamine receptors the way oral antihistamines do.

Where is OmneDiem based?

OmneDiem is headquartered in Ann Arbor, Michigan, and ships across the U.S. and U.S. territories.

Combat Histamine Sensitivity & Enhance Digestion

Designed for those sensitive to histamine, Histamine Digest family of product help mitigate histamine-induced discomfort before it starts. Whether you're sensitive to aged cheeses, fermented foods, red wine, or cured meats, this supplement provides essential support to ease gastric distress, inflammation, and other histamine-related symptoms, ensuring greater meal tolerance.