Introducing OmneDiem Superzymes: A Full-Spectrum Digestive Enzyme with Betaine HCl
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From the OmneDiem team · New Products · About a 6-minute read
New from OmneDiem
OmneDiem Superzymes is a full-spectrum multi-enzyme formula that supports digestion from start to finish.† Each tablet combines betaine HCl, pepsin, pancreatin, ox bile extract, bromelain and papain to support the breakdown of proteins, fats and carbohydrates, and to help ease occasional gas, bloating and fullness after meals.† It comes in a 180-tablet bottle for $39.99, or $35.99 with Subscribe & Save.
What is OmneDiem Superzymes?
Superzymes is our first full-spectrum digestive enzyme. Most people know OmneDiem for our DAO enzymes, which support the breakdown of histamine from food.† Superzymes takes on a bigger job: supporting the digestion of the meal itself.
| Product | OmneDiem Superzymes Multi-Enzyme with Betaine HCl |
|---|---|
| Format | 180 tablets |
| Key ingredients | Betaine HCl, pepsin, pancreatin, ox bile extract, bromelain, papain |
| Supports | Digestion of proteins, fats and carbohydrates; healthy stomach acid levels; nutrient absorption† |
| How to take | At the start of meals, or as directed on the label; never on an empty stomach |
| Price | $39.99, or $35.99 with Subscribe & Save (10% off) |
| Shipping | Free in the US |
| Dietary note | Contains animal-derived enzymes; not vegetarian or vegan |
| Made by | OmneDiem, Ann Arbor, Michigan |
Product details from omnediem.com, October 2026.
Why did OmneDiem create a full-spectrum digestive enzyme?
Think of a meal as a relay race. Stomach acid and pepsin run the first leg, bile hands off the fats, and pancreatic enzymes carry everything across the finish line. When one runner slows down, the whole race suffers, and food can move on only partly digested.
Stomach acid output can decline with age and with regular use of acid-reducing products. Yet many enzyme blends start at the second leg and skip the stomach entirely. We wanted one tablet that supports every leg of the race, so we built Superzymes around betaine HCl and pepsin, then added pancreatin, ox bile and plant enzymes.†
What are the benefits of Superzymes?
- Supports complete digestion of proteins, fats and carbs†
- Supports healthy stomach acid levels†
- Helps ease occasional gas, bloating and fullness†
- Supports absorption of calcium, B12, folate and iron†
- Supports digestion of rich, fatty meals†
What ingredients are in Superzymes?
Now available
Meet Superzymes: digestive support from the first bite
180 tablets · Subscribe & Save 10% · Free US shipping
Who is Superzymes for?
Superzymes may be a good fit for:
- Older adults, since stomach acid output can decline with age
- People who eat protein-rich or high-fat meals
- Anyone who feels heavy or uncomfortable after eating†
How is Superzymes different from OmneDiem's DAO enzymes?
They do different jobs. Superzymes supports the digestion of proteins, fats and carbohydrates. Our DAO enzymes support the breakdown of histamine from food.†
| Superzymes | Histamine Digest (DAO) | |
|---|---|---|
| Main job | Supports digestion of proteins, fats and carbs† | Supports breakdown of dietary histamine† |
| Key ingredients | Betaine HCl, pepsin, pancreatin, ox bile, bromelain, papain | DAO enzyme, 30,000 HDU per capsule |
| May fit if | Heavy or rich meals leave you full, gassy or sluggish | Reactions follow aged cheese, wine, leftovers or fermented foods |
| Learn more | Shop Superzymes | Shop Histamine Digest |
Thinking about using both? Talk with your healthcare provider before combining supplements.
How do I take Superzymes?
Take Superzymes at the start of meals, or as directed on the label. Do not take it on an empty stomach. Many people start with their heaviest meal of the day.
Who should not take Superzymes?
Because Superzymes contains betaine HCl, do not use it if you have a history of ulcers, or if you take NSAIDs, steroids or acid-reducing medications, without first talking with your healthcare provider.
Superzymes contains animal-derived enzymes, so it is not suitable for vegetarians or vegans.
Where can I buy Superzymes, and how much does it cost?
Superzymes is available now at omnediem.com. A 180-tablet bottle is $39.99, about 22 cents a tablet. With Subscribe & Save, it is $35.99, about 20 cents a tablet, and shipping is free in the US.
Digestion, start to finish
OmneDiem Superzymes Multi-Enzyme with Betaine HCl · 180 tablets
Subscribe & Save 10% · Free US shipping
Shop SuperzymesWhat else do people ask about Superzymes?
What is OmneDiem Superzymes?
Superzymes is a full-spectrum multi-enzyme formula with betaine HCl, pepsin, pancreatin, ox bile, bromelain and papain that supports digestion of proteins, fats and carbs.†
What is betaine HCl?
Betaine HCl is a mild form of hydrochloric acid that supports stomach acidity and the beginning of protein digestion.†
Can Superzymes help with bloating?
By supporting thorough digestion, Superzymes helps ease occasional gas, bloating and that heavy feeling after meals.†
When should I take Superzymes?
Take it at the start of meals, or as directed on the label. Do not take it on an empty stomach.
Is Superzymes vegetarian?
No. Superzymes contains animal-derived pepsin, pancreatin and ox bile extract, along with plant-derived bromelain and papain.
How much does Superzymes cost?
A 180-tablet bottle is $39.99 on omnediem.com, or $35.99 with Subscribe & Save. Shipping is free in the US.
Related resources
- Best Digestive Enzyme Supplements for Bloating and Gas: How to Choose Compare enzyme types, from lactase to multi-enzyme formulas, and match one to the meals that leave you bloated.
- Best Digestive Enzyme for Low Stomach Acid and Poor Protein Digestion Why protein digestion starts with stomach acid, what betaine HCl and pepsin do, and who should skip them.
- Best Value Full-Spectrum Digestive Enzyme Supplement: How to Compare Cost and Coverage How to compare enzymes on cost per serving and coverage, with the value math for Superzymes.
Scientific references
- Ianiro G, Pecere S, Giorgio V, Gasbarrini A, Cammarota G. Digestive enzyme supplementation in gastrointestinal diseases. Curr Drug Metab. 2016;17(2):187-193.
- Yago MR, et al. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Mol Pharm. 2013;10(11):4032-4037.
- Roxas M. The role of enzyme supplementation in digestive disorders. Altern Med Rev. 2008;13(4):307-314.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prices are from omnediem.com as of October 2026 and are subject to change.