Fructose Malabsorption can be a real pain in the gut.
OmneDiem® Fructose Digest can help.*
OmneDiem Fructose Digest which supplies Xylose Isomerase (XI). Avoiding fructose-laden foods and adhering to a low FODMAP1 diet can be difficult, inconvenient, limiting and less pleasurable. Therefore, Diem Fructose Digest is the best option for managing fructose malabsorption.*
XI is a natural bacterial enzyme that transforms fructose to glucose, which is easily absorbed
Take prior to the consumption of high-fructose foods and beverages
Active only in the GI tract and is not absorbed into the body, making it remarkably safe for daily use
What is Fructose and Fructose Malabsorption?
Fructose is a hexose (simple sugar). Fructose Malabsorption (FM) is the incomplete absorption of free dietary fructose in the small intestine, which thus allows migration of fructose into the small intestine and colon. When this occurs, fructose interacts with bacteria in the gut, producing physical discomfort and contributing to weight gain, lipid irregularities, and more.
- Sugar soft drinks (20 oz) - 20-30 grams
- Large apple - 13 grams
- 20 grapes - 7 grams
- 1 tsp honey - 8 grams
- 1 banana - 5 grams
What is the mechanism of Fructose Malabsorption?
Fructose is well absorbed in the presence of glucose. Free fructose without corresponding glucose, however, is poorly absorbed. The signs of Fructose Malabsorption appear when the activity of its transport protein GLUT5 is impaired, and bacteria are able to ferment the fructose before absorption. While glucose is efficiently and near completely absorbed in the small intestine, fructose is not.
Prevalance Fructose Malabsorption
The Food Intolerance Institute reports up to 33% of the population are affected by fructose malabsorption. In a 2005 report in the Journal of the Academy of Nutrition and Dietetics, researchers determined fructose malabsorption, as defined by the appearance of hydrogen in the breath after an oral load of fructose, is common. The frequency is dependent upon how much fructose is given; 53% of people will incompletely absorb a 25 g load, while 73% of people will incompletely absorb with a 50 g load.
A 2008 study ofAmerican children and adults reported a nearly 50% Increase in fructose consumption from 1977-1994.
Vos MB, et al.; Medscape J Med. 2008;10(7):160.
Defect Fructose Resorption (Fructose Malabsorption)
As a consequence of impaired absorption, fructose reaches the colon and is metabolized by colonic bacteria. The byproducts hydrogen, carbon dioxide, methane, short-chain fatty acids (SCFA), and osmotic water influx cause the typical reactions. Reactions can occur up to 2 hours after consuming fructose; however, timing can vary based on individual circumstances.
Identification and Management of Fructose Malabsorption
The reactions to fructose malabsorption are similar to those for lactose intolerance and other food intolerances. Fortunately, a hydrogen breath test is a non-invasive way to identify issues with fructose digestion. Avoiding or eliminating fructose-laden foods, in addition to other dietary modifications, will also help identify and manage fructose malabsorption. Supplementation with the digestive enzyme Xylose Isomerase can be a useful adjunct strategy to promote optimal fructose absorption.*
- Abdominal Pain
- Chronic Fatigue
- Sugar Cravings
- Fructose carrier deficiency
- Imbalance of good and bad gut bacteria
- High intake of refined and processed foods
- Pre-existing gut issues
- Fructose Malabsorption is linked to other gut issues and mood disturbances.
- Excessive fructose consumption may have significant effects on lipid metabolism and lipid homeostasis.
How does OmneDiem® Fructose Digest Work?
OmneDiem™ Fructose Digest (Xylose Isomerase) provides the enzyme that catalyzes the conversion of poorly absorbable fructose into well-absorbable glucose in the human intestine. Presented in a patented designed-release capsule to ensure enteric delivery, Fructose Digest supports the conversion of dietary fructose to defend against the discomfort of malabsorption reactions.*
DOES NOT CONTAIN: Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.