Natural Menopause Support Supplements

DAO Enzyme + Hormonal & Cognitive Support

OmneDiem® Menopause Complete with DAO Plus is a daily, multi-action dietary supplement formulated to support women through the menopausal transition — combining diamine oxidase (DAO) for the body's natural histamine metabolism with botanicals and citicoline to help support hormonal balance and everyday mental clarity.*

  • 15,000 HDU DAO
  • Non-GMO
  • Gluten-Free
  • Soy-Free
  • No Unnecessary Fillers
  • Designed-Release Capsule
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Why Menopause Complete

During the menopausal transition, shifting hormones may influence how efficiently the body manages histamine. Research describes a relationship between estrogen and the histamine-clearing enzyme DAO — estrogen may down-regulate DAO activity (female sex hormones & DAO). Menopause Complete is built around supplemental DAO to support the body's natural histamine breakdown in the gut, then adds targeted botanicals and a nootropic so one capsule supports three areas at once.*

  • Natural Histamine MetabolismSupplies 15,000 HDU of DAO to support the body's breakdown of dietary histamine in the digestive tract.*
  • Menopausal-Transition SupportEstro8PN® hops, flax lignans & black cohosh chosen to help support hormonal balance and a healthy mood.*
  • Mental ClarityCiticoline to support focus, memory, and everyday cognitive energy.*
  • Clean, Considered FormulaNon-GMO, gluten-free, soy-free, with no unnecessary fillers.*
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What's Inside

Ingredient What it's included to support*
Diamine Oxidase (DAO), 15,000 HDU Supports the body's natural breakdown of dietary histamine in the digestive tract*
Estro8PN® hops extract (8-prenylnaringenin) A hops-derived phytoestrogen studied for supporting comfort during the menopausal transition*
Flaxseed extract (lignans) Plant lignans that help support the body's natural hormone metabolism*
Black cohosh A botanical traditionally used to support comfort and a healthy mood during menopause*
Citicoline Supports focus, memory, and mental clarity*

Botanical context: a randomized, double-blind, placebo-controlled pilot study explored a standardized hop extract for menopausal comfort (Erkkola et al., 2010), and 8-prenylnaringenin is recognized as a potent plant phytoestrogen (&Štulíková et al., 2018).*

How to Use

Take as directed on the label. Many people take Menopause Complete daily, and before high-histamine foods or beverages, to help support DAO activity where dietary histamine is processed. The designed-release capsule is formulated to activate in the small intestine. Consult your healthcare provider before use, especially if pregnant, nursing, taking medications (including hormone therapy), or managing a health condition.*

Who It's For

Women navigating perimenopause and the menopausal transition who want all-in-one support: DAO for the body's natural histamine metabolism, botanicals for hormonal balance, and citicoline for mental clarity — in a single clean-label capsule. Looking for DAO enzyme support on its own? Browse the full range of OmneDiem® DAO supplements.*

Frequently Asked Questions

Can menopause affect histamine and DAO?

Research describes a relationship between estrogen and the histamine-clearing enzyme DAO: estrogen may down-regulate DAO activity, and DAO levels shift alongside hormones across the menstrual cycle (menstrual cycle & serum DAO, 2012). This is educational information, not a diagnosis.*

What does the DAO in Menopause Complete do?

It supplies diamine oxidase (DAO) to support the body's natural breakdown of dietary histamine in the digestive tract.* It is not intended to diagnose, treat, cure, or prevent any condition.

Is this hormone replacement therapy (HRT)?

No. Menopause Complete is a dietary supplement formulated to support the body's natural processes during the menopausal transition. It is not a drug, not HRT, and is not intended to diagnose, treat, cure, or prevent any disease.*

Is Estro8PN® the same as estrogen?

No. Estro8PN® is a standardized hops extract providing 8-prenylnaringenin, a plant phytoestrogen — a botanical compound, not a hormone medication — included to support the body during this natural life stage.*

Is it suitable for vegetarians or vegans?

No. The DAO in this formula is porcine-derived, so it is not suitable for those with pork allergies or following vegetarian, vegan, kosher, or halal diets.*

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or health condition. The terms "menopause," "perimenopause," and "histamine intolerance" are used for educational purposes only. Individual results may vary. OmneDiem® Menopause Complete with DAO contains a porcine-derived DAO ingredient — not suitable for individuals with pork allergies or those following vegetarian, vegan, kosher, or halal diets. Not for use during pregnancy or breastfeeding without prior consultation with your healthcare provider. Keep out of reach of children.