25% For 2025. 25% Off Histamine Digest with code NEWYEAR25

25% For 2025. 25% Off Histamine Digest with code NEWYEAR25

OmneDiem
  • Shop
  • About Us
  • Where to Buy
  • Blog
  • Contact Us
Login / Register
Search
0 Wishlist
1 item $29.95
Menu
OmneDiem
1 item $29.95
“Histamine Complete 30 Caps” has been added to your cart. View cart
OmneDiem SAMe S-Adenosylmethionine
Click to enlarge
OmneDiem SAMe S-Adenosylmethionine
Home Shop All Products SAMe 30 Tablets
OmneDiem Metabolic Support New Look bottle
Metabolic Support with Adiposano 60 Capsules $49.95 — or subscribe and save 6%
Back to products
OmneDiem Joint Comfort 60 Capsules
Joint Comfort with Zoara 60 Capsules $39.95 — or subscribe and save 6%

SAMe 30 Tablets

$63.95 — or subscribe and save 6%

In stock

Deliver:

The longer you stay subscribed the more you save.

Subscriptions Delivered Discount (%) Price
1 - 2 — $63.95
3 - 6 10 % $57.56
7+ 15 % $54.36

The longer you stay subscribed the more you save.

Subscriptions Delivered Discount (%) Price
1 - 2 — $60.11
3 - 6 10 % $54.10
7+ 15 % $51.10

The longer you stay subscribed the more you save.

Subscriptions Delivered Discount (%) Price
1 - 2 — $60.11
3 - 6 10 % $54.10
7+ 15 % $51.10

The longer you stay subscribed the more you save.

Subscriptions Delivered Discount (%) Price
1 - 2 — $60.11
3 - 6 10 % $54.10
7+ 15 % $51.10

Compare
Add to wishlist
SKU: SAM30 Categories: All Products, Joint Care
Share:
  • Description
  • Additional information
  • Reviews (0)
  • Shipping & Delivery
Description

Omne Diem SAMe header

OmneDiem SAMe. S-Adenosylmethionine (SAMe) is a naturally occurring compound found in almost every tissue and fluid in the body. It is involved in many important processes associated with mood, joints, and liver.*

Dietary Support for Joint Comfort, Mood, and Liver Health*

Mood Support

SAMe supplementation helps support sustained emotional well-being by promoting the production and break down of brain chemicals, such as serotonin, melatonin, and dopamine.*

Liver Health

Liver Health

SAMe helps restore and maintain healthy liver functions and detoxification by converting into glutathione; helping the liver combat oxidative stress, cellular damage, free radical activity and DNA breakdown.*

Joint Comfort

Joint Comfort

SAMe supplementation helps support cartilage and joint comfort and function by promoting native proteoglycan synthesis and secretion as well as other mechanisms.*

Why OmneDiem SAMe?

Stability and Safety

Stability and Safety

  • Formulated with Pharmaceutical Grade S-Adenosylmethionine Butanedisulfonate (SAMe) which is more stable on the (S,S) Isomer.
  • Packaged in individual tamper-proof foil blister-packed to maximize stability and safety.
Bioavailability

Bioavailability

  • Made naturally by microbiological fermentation and specially processed in an ultra-low moisture and temperature controlled clean-room to preserve 68-80% (S,S) SAMe, the highest active level available.
  • Plant based enteric coating is formulated to pH release in the small intestine for maximum bioavailability and absorption.
GI Friendly

GI Friendly

  • The plant-based enteric coating used in OmneDiem’s SAMe is designed to help reduce allergic reactions, stomach and gastrointestinal irritation and upset.
  • Does not contain harsh chemicals, synthetic color and plastic co-polymer coating excipients included in other SAMe products.

 

Additional information
Weight 1.64 oz
Dimensions 6 × 4 × 1.25 in
Reviews (0)

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Shipping & Delivery

United States shipping methods and delivery ETAs: 

  • Standard shipping (via USPS): 7 business days after the item ships  
  • UPS Ground shipping: 3-5 business days after the item ships
  • UPS Next Day/2nd Day Air: guaranteed same day shipment if your order is placed on a business day by 11am, Central Standard Time; all Air orders entered after this time will ship the next business day 
  • Your order will generally be shipped the same day if your order is placed by 11am, Central Standard Time. If your order is placed after that time, or on a non-business day, your order will ship the next business day. No C.O.D. will be accepted.
  • Business Days are Monday through Friday.
  • If a package is delayed in transit, customers must allow 30 days from date of shipment before OmneDiem can provide further assistance.
  • UPS and FedEx cannot ship to PO Boxes.

International shipping methods and delivery ETAs: 

  •  UPS Worldwide Expedited: 7-10 business days after the item ships.
  • USPS First Class International (North America only): up to 20 business days after the item ships.
  • Your order will generally be shipped the same day if your is placed by 11am Central Standard Time. If your order is placed after that time, or on a non-business day, your order will ship the next business day. No C.O.D. will be accepted.
  • Delivery time frames do not include any time the package may be in possession by your local Customs bureau, only the time in transit by the carrier.
  • Business Days are defined as Monday through Friday.
  • If a package is delayed in transit, customers must allow 60 days from date of shipment before OmneDiem can provide further assistance.
  • All International orders must ship within the country associated with the billing address. No dropships allowed.*
    *Exception for orders shipped within North America

ATTENTION NORTH AMERICAN CUSTOMERS: USMCA and Changes to De Minimis:

The United States-Mexico-Canada Agreement is the treaty replacing NAFTA as of July 1st, 2020.

A significant change was made to the de minimis threshold for international shipments. De minimis is the minimum value of goods item below which no duties and/or taxes are assessed by Customs.

The new de minimis value thresholds for commercial shipments (i.e., UPS) into Canada and Mexico:

  • The new Mexico de minimis threshold is $117 USD for duty and $50 USD for taxes.
  • The new Canada de minimis threshold is $150 CAD for duty and $40 CAD for taxes, only for shipments exported directly from the U.S. or MX (for CA only).
  • The U.S. threshold for importation remains at $800 USD.

For shipments traveling via a postal method (i.e., USPS), the threshold is $300 USD.

  • If the value of the merchandise is $300 USD or less, it is free of any tax or duty under most circumstances. A commercial invoice is preferred, but not required for merchandise valued up to $300 USD.
  • For merchandise with a value over $300 USD and up to $1,000 USD, duties and taxes may apply and a commercial invoice is required.

ATTENTION INTERNATIONAL CUSTOMERS:

  • Please note:  Import duties, taxes and charges are not included in the item price or shipping cost. These charges are the buyer’s responsibility. Please check with your country’s customs office to determine what these additional costs will be prior to buying. Buyer’s failure to accept delivery (including in the event of buyer’s failure to accept delivery from customs owing to import duties, taxes or charges) may, in our sole discretion, mean that the products are not eligible for any refund of buyer’s original payment.  If we do accept a return, any refunds related to such product returns, will be reduced by the shipping costs associated with the returned products.

Related products

OmneDiem Histamine Digest 15HDU Histamine Intolerence DAO Deficiency 30 count
Compare

Histamine Digest with DAO 15,000 HDU/2.1mg 30 Caps

$19.95
OmneDiem Histamine Digest® with 15,000 HDUs, supplies Diamine Oxidase (DAO), the enzyme that neutralizes histamine in the digestive tract.* Taking OmneDiem Histamine Digest® prior to consuming high histamine foods and beverages helps defend against digestive histamine sensitivity and the occurrence of accompanying reactions.*
Add to wishlist
Add to cart
OmneDiem Histamine Digest Menopause Complete
OmneDiem Histamine Digest Menopause Complete Supplement Facts
Compare

Menopause Complete 30 Capsules

$39.95
OmneDiem® Histamine Digest® Menopause Complete supports the body’s healthy response to the natural changes occurring during menopause. The addition of DAO supports natural histamine levels and processing which are impacted by hormonal fluctuations.*
  • Support for Your Comfort and Well-Being*
  • 15,000 HDU
  • Part of the Histamine Digest® Family of Products
Add to wishlist
Add to cart
OmneDiem Histamine Digest PureMAX DAOgest
OmneDiem Histamine Digest PureMAX 40,000 HDU 60 capsules - supplement facts
Compare

Histamine Digest PureMAX with DAO 60 Capsules

$54.95 — or subscribe and save 6%
Rated 5.00 out of 5
For those with multiple sensitivities and higher Diamine Oxidase (DAO) needs,  OmneDiem® Histamine Digest® PureMAX, our purest formulation to date. Now with 40,000 HDU, due to advancements in the extraction and manufacturing process.*  
Add to wishlist
Add to cart
OmneDiem Metabolic Support New Look bottle
Compare

Metabolic Support with Adiposano 60 Capsules

$49.95 — or subscribe and save 6%
Rated 5.00 out of 5
Metabolic Support with Adiposano is a supplement indicated for the dietary management of individuals with excess white adipose tissue and metabolic-related joint health concerns.
Add to wishlist
Add to cart
OmneDiem Connective Tissue TLC
OmneDiem Connective Tissue TLC Supplement Facts
Compare

Connective Tissue TLC (192 grams/6.77 oz)

$66.50
OmneDiem® Connective Tissue TLC (Tendons, Ligaments and Cartilage) combines 3 clinically studied ingredients that provide optimum nutrition to connective tissue, regardless of whether that tissue is healthy or compromised.*
Add to wishlist
Add to cart
OmneDiem Brain Support Plus 30 Capsules
OmneDiem Brain Support Plus 30 Capsules Supplement Facts
Compare

Brain Support + 30 Capsules

$29.95 — or subscribe and save 6%
Brain Support Plus (sodium citicoline) is a dietary supplement indicated for the distinct nutritional needs of those experiencing age-related cognitive decline and related concerns. Now available in a smaller 30 capsule bottle!
Add to wishlist
Add to cart
OmneDiem Floof Fuel
OmneDiem Guaranteed Analysis
Compare

Floof Fuel for Dogs and Cats 7 oz

$19.95 — or subscribe and save 6%
Floof Fuel™ Pure Norwegian Bone Broth by OmneDiem is a delicious, powdered poultry pet food topper sure to delight any canine or feline. A portion of all Floof Fuel sales will be converted into Floof Fuel donations to local animal shelters. Ounces Donated to Shelters to date: 1888
Add to wishlist
Add to cart
OmneDiem Pure Norwegian Bone Broth
OmneDiem Pure Norwegian Bone Broth label
Compare

Pure Norwegian Bone Broth 180 Grams/6.35 Ounces

$19.95 — or subscribe and save 6%
A pure source of Paleo & Keto friendly hydrolyzed protein & collagen peptides. 
Add to wishlist
Add to cart

    Diem Direct Supplements to Seize The Day

    221 Dino Drive, Ann Arbor, MI 48103
    customerservice@omnediem.com
    Customer Service: (888) 876-5765

    Customer Service Hours:
    Monday – Friday 9am-5pm EST.

    Useful links
      • Shipping & Return Policy
      • Subscriptions
      • Privacy Policy
      • Terms & Conditions
      • About Us
      • Affiliate Login
      • Blog

    *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseases.

    All rights reserved OmneDiem 2025
    • Menu
    • Categories
    • Find Your Product
    • Shop
    • About Us
    • Where to Buy
    • Blog
    • Contact Us
    • Wishlist
    • Compare
    • Login / Register
    Sign in
    Close

    Lost your password?

    No account yet?

    Create an Account
    Facebook Instagram Pinterest linkedin TikTok
    We use cookies to improve your experience on our website. By browsing this website, you agree to our use of cookies.
    More info More info Accept
    Start typing to see products you are looking for.
    Shop
    0 Wishlist
    1 item Cart
    My account