Histamine Digest Family

OmneDiem® has built the most comprehensive family of Diamine Oxidase (DAO) enzyme dietary supplements available in the U.S. market today. Each product in the Histamine Digest® family is formulated around DAOgest® — a naturally derived, porcine-sourced DAO enzyme — and designed to support the body's natural histamine breakdown process in the gut when taken before consuming high-histamine foods and beverages.* Whether you're looking for everyday support, maximum potency, broader histamine coverage, menopausal wellness support, or alcohol related histamine intolerance, there is a Histamine Digest® formulation designed for your needs.

OmneDiem® Histamine Digest® - 30 capsules

The original, foundational DAO enzyme supplement — now available in a 30-capsule starter size. Each designed-release capsule supplies 30,000 HDU of DAOgest® DAO, formulated to activate in the small intestine where dietary histamine is processed.* A 30-capsule supply is ideal for those who are exploring DAO supplementation for the first time, want to travel light, or prefer a shorter initial commitment before stocking up.*

• Active ingredient: DAOgest® (porcine-derived DAO) — 15,000 HDU per capsule
• Format: Designed-release capsule; do not open or crush
• Suggested use: Take 1 capsule before consuming high-histamine foods or beverages*
• Free from: Gluten, GMOs, artificial colors, preservatives
• Count: 30 capsules

OmneDiem® Histamine Digest® -60 capsules

The same trusted 30,000 HDU Histamine Digest® formulation in a 60-capsule supply — a popular choice for consistent everyday use.* The 60-count format offers a full two-month supply for those using one capsule daily before a main meal, or approximately one month's supply for those taking two capsules on higher-histamine days.*

• Active ingredient: DAOgest® (porcine-derived DAO) — 15,000 HDU per capsule
• Format: Designed-release capsule
• Suggested use: Take 1 capsule before consuming high-histamine foods or beverages*
• Free from: Gluten, GMOs, artificial colors, preservatives
• Count: 60 capsules

OmneDiem® Histamine Digest®

The best-value size in the Histamine Digest® line — 120 capsules of 30,000 HDU DAOgest® DAO for those who have made Histamine Digest® a consistent part of their daily wellness routine.* The 120-count format is the most economical per-capsule option and ensures you never run out at an inconvenient moment.*

• Active ingredient: DAOgest® (porcine-derived DAO) — 15,000 HDU per capsule
• Format: Designed-release capsule
• Suggested use: Take 1 capsule before consuming high-histamine foods or beverages*
• Free from: Gluten, GMOs, artificial colors, preservatives
• Count: 120 capsules

OmneDiem® Histamine Digest® PureMAX

OmneDiem's highest-potency DAO formulation — and the purest. Each designed-release capsule supplies 40,000 HDU of DAOgest® DAO with absolutely no added excipients beyond ultra-purified microcrystalline cellulose (MCC). PureMAX was formulated for those who benefit from a higher level of DAO enzyme support, whether due to greater dietary histamine intake, reduced natural DAO activity, or the desire for maximum potency in the cleanest possible delivery.*

PureMAX delivers more than 2.5 times the DAO activity per capsule compared to the standard Histamine Digest® formulation — making it OmneDiem's most powerful option for dietary histamine management.*

• Active ingredient: DAOgest® (porcine-derived DAO) — 40,000 HDU per capsule
• Format: Designed-release capsule; do not open or crush
• Suggested use: Take 1 capsule before consuming high-histamine foods or beverages*
• Excipients: Ultra-purified MCC only — nothing else
• Free from: Gluten, GMOs, artificial colors, preservatives, unnecessary additives
• Count: 60 capsules

OmneDiem® Histamine Digest® Menopause Complete  

The newest and most comprehensive addition to the Histamine Digest® family — and the only product that addresses the intersection of hormonal changes and histamine sensitivity in a single daily capsule.* OmneDiem® Histamine Digest® Menopause Complete supports the body's healthy response to the natural changes occurring during menopause. The addition of DAO supports natural histamine levels and processing which are impacted by hormonal fluctuations.*

As estrogen levels fluctuate during perimenopause and decline in menopause, the body's natural DAO enzyme activity may be affected — which may be associated with new or changing responses to high-histamine foods and beverages.* Menopause Complete addresses this directly by combining DAO with four additional evidence-informed ingredients that support women's comfort and well-being through this hormonal transition.*

The five-ingredient formula includes:

• DAOgest® (DAO Enzyme) — 15,000 HDU: supports the body's natural histamine breakdown process in the gut*
• Estro8PN® (8-Prenylnaringenin from Hops): a patented, standardized phytoestrogen studied for its role in supporting hormonal comfort during the menopausal transition*
• Flaxseed Extract (40% Lignan): plant-derived compounds that may support healthy hormonal balance during menopause*
• Black Cohosh: a traditional botanical with a long history of use in women's wellness support during hormonal transitions*
• Citicoline: a clinically studied compound that may support brain energy, mental clarity, and cognitive function during menopause*
• Format: Capsule; take once daily
• Suggested use: Take 1 capsule daily; also take before consuming high-histamine foods or beverages for DAO support*
• Free from: Gluten, soy, GMOs, artificial additives
• Count: 30 capsules (30-day supply)

Menopause Complete is part of the Histamine Digest® family and contains porcine-derived DAOgest®.

OmneDiem® Histamine Complete

The only product in the OmneDiem® family formulated to support both dietary and environmental histamine pathways.* Histamine Complete combines 15,000 HDU of DAOgest® DAO — the same designed-release enzyme delivery found in Histamine Digest® — with additional ingredients that support healthy seasonal respiratory and sinus function and a balanced histamine response throughout the body.* It is the first formulation of its kind in U.S. retail.*

Histamine Complete is designed for those who are not only sensitive to high-histamine foods and beverages but who also want daily support for the body's broader histamine balance, including during seasonal environmental changes.* Take daily as part of your wellness routine, and also before high-histamine meals and beverages.*

• Active ingredients: DAOgest® (porcine-derived DAO) — 15,000 HDU + additional histamine-balancing support ingredients*
• Format: Capsule
• Suggested use: Take daily for ongoing support; also take before high-histamine meals or beverages*
• Free from: Gluten, GMOs, artificial colors, preservatives
• Count: 30 capsules

OmneDiem® Drink HD 

While not branded under the Histamine Digest® name, Drink HD is part of OmneDiem's broader DAO enzyme supplement family. Drink HD is specifically formulated for pre-drinking use — supplying DAOgest® DAO in a compact, portable 20-capsule tube designed to be taken before consuming alcoholic beverages.* Alcoholic beverages — particularly red wine, craft beer and aged spirits— are among the highest-histamine items many people regularly consume, and alcohol itself may affect the body's natural DAO activity.*

• Active ingredient: DAOgest® (porcine-derived DAO) — 15,000 HDU per capsule
• Format: Designed-release capsule; portable 20-count tube
• Suggested use: Take 1 capsule before consuming alcoholic beverages*
• Count: 20 capsules per tube

Which Histamine Digest® Product Is Right for You?

Consult your healthcare provider to determine which product or combination may be most appropriate for your individual needs. Browse the full OmneDiem® Histamine Digest® family at omnediemdirect.com/collections/histamine-digest

For educational resources, FAQs, and clinical background on DAOgest® and DAO supplementation, visit omnediem.com/faq and omnediem.com/an-honest-evaluation.

* These statements have not been evaluated by the Food and Drug Administration. OmneDiem® dietary supplements are not intended to diagnose, treat, cure, or prevent any disease or health condition. Product descriptions are for general informational purposes only. Individual results may vary. Suggested use information is not a substitute for the product label — always read and follow label directions. Menopause Complete contains phytoestrogenic ingredients; women who are taking hormone replacement therapy, have a history of estrogen-sensitive conditions, or are on anticoagulant medications should consult their healthcare provider before use. Consult your healthcare provider before beginning any new supplement regimen, particularly if you are pregnant, nursing, taking prescription medications, or managing a health condition. All OmneDiem® Histamine Digest® products contain a porcine-derived ingredient (DAOgest®) and are not suitable for individuals with pork allergies or those following vegetarian, vegan, kosher, or halal diets. Keep all dietary supplements out of reach of children.